CanVIG-UK Consensus Specification for Cancer Susceptibility Genes ACGS Best Practice Guidelines for Variant Classification (v2.18) · v2.18 · Approved: 28/09/2023.

Training and education. Detailed specification for germline cancer genetics of the UK-ACGS Best Practice Guidelines for Variant Interpretation ...

3 мар 2020 · ... guidelines but referencing data inputs specific to cancer susceptibility genes. Evidence and guidance are dynamic; regular updated versions ...

3 мар 2020 · CanVIG-UK specification, we shall include specific recommendations regarding adoption and implementation of these disease/gene specific-guidance ...

18 ној 2020 · ... CanVIG-UK and ClinGen gene-specific guidance for PTEN, TP53 and CDH1). We present consensus recommendations from CanVIG-UK regarding (1) ...

Ongoing work seeks to improve these guidelines, including the generation of versions specific for particular conditions and specific guidelines for ...

Locus- specific databases and recommendations to strengthen their contribution to the classification of variants in cancer susceptibility genes. Hum Mutat. 2008 ...

18 ној 2020 · Combining evidence for and against pathogenicity for variants in cancer susceptibility genes: CanVIG-UK consensus recommendations · Abstract.

Ratification of additional guidance in germline cancer genetics relevant to the UK clinical-laboratory community. Historically, the first presentation to the ...

5 мар 2024 · The UK Association for Clinical Genomic Sciences (ACGS) routinely publishes updated best practice guidelines for variant interpretation, ...