Progesterone receptor (PR) gene on chromosome 11 encodes PR protein · Member of hormone receptor family of ligand dependent transcription factors. Essential ...

16 нояб. 2022 г. · PR is dependent on estrogen for its expression, upregulated by ER and modulates the behavior of ER (Nature 2015;523:313) · > 80% of ER positive ...

16 апр. 2024 г. · Classic functions of ER; May render breast epithelium susceptible to proliferative stimulation of estrogen; Expressed in breast and endometrium.

23 янв. 2024 г. · Molecular subtypes · ER negative, PR negative, HER2 negative, includes high and low grade tumors · Broken down into basal-like type 1, basal-like ...

HER2 gene amplification / protein overexpression · Present in approximately 15 - 20% of breast tumors · Associated with comedocarcinoma and aggressive invasive ...

1 мая 2024 г. · Medullary pattern is a histological pattern that can be applied to an invasive breast carcinoma of no special type that contains pushing ...

Androgen receptor (AR) is a member of the superfamily of ligand responsive transcription regulators; It functions in the nucleus where it is believed to act ...

20 сент. 2021 г. · PR (0 - 30%) (Breast Cancer Res Treat 2013;141:1); CK7 negative Paget disease is rare and can be a diagnostic pitfall (Pathol Res Pract 2016 ...

Pathology Outlines is a multi-authored online textbook covering a wide range of topics with macroscopic and microscopic pathology images.

Mucinous cystadenocarcinoma: Cribriform, papillary or micropapillary carcinoma lining the cysts with mucin production; ER and PR-. Invasive micropapillary ...