Knockout sgRNA AAV Library. We offer All-in-One and sgRNA only AAV vector/viruses for knockout of any human, mouse, or rat gene.

This AAV CRISPR knockout library targets mouse tumor suppressor genes (TSG). Each plasmid carries one TSG-targeting sgRNA in addition to one p53-targeting sgRNA ...

We found that the AAV-mTSG CRISPR library resulted in more robust gliomagenesis in vivo compared to lentiCRISPR mTSG, in terms of latency (death of first animal ...

CRISPR pooled libraries consist of thousands of plasmids, each containing multiple gRNAs for each target gene.

We developed a strategy for screening in the mouse brain called “CRISPR screening by AAV episome sequencing” (CrAAVe-seq). Incorporating a Cre recombinase-based ...

In this webinar, Thomas Quinn discusses the design and execution of genome-wide CRISPR/Cas9-based knockout screens using pooled lentiviral sgRNA libraries.

In this study, we performed two pooled, genome-wide screens to identify positive and negative factors modulating AAV2 transduction.

Order AAV CRISPR vectors from VectorBuilder for achieving AAV-mediated CRISPR genome editing in mammalian cells and animals starting at only $99.

Pooled CRISPR guide RNA libraries, or gRNA libraries, are ideal for high-throughput screening of important molecular targets.

30 сент. 2019 г. · In this study, we observe high levels of AAV integration (up to 47%) into Cas9-induced double-strand breaks (DSBs) in therapeutically relevant genes.