Mechanism of Action:
Amantadine interferes with the release of infectious viral nucleic acid into the host cell through interaction with the transmembrane domain of the M2 protein of the virus . It also appears to prevent virus assembly during replication in some cases.
The mechanism of its antiparkinsonic effect is not fully understood, but it appears to be releasing dopamine from the nerve endings of the brain cells, together ... Identification · Pharmacology · Interactions · Products |
The antiviral mechanism of action is inhibition of the influenza virus A M2 proton channel, which prevents endosomal escape (i.e., the release of viral genetic ... Medical uses · Side effects · Interactions · Pharmacology |
Its mechanism of action involves inhibition of the transmembrane domain of the viral M2 protein, thus preventing viral uncoating during early stages of ... |
Amantadine is an agent that raises the concentration of dopamine in the synaptic cleft by releasing it from neurons and suppressing the process of reuptake. |
The most likely effects of amantadine to be important in the alleviation of Parkinsonian symptoms are an indirect dopamine-releasing action and a direct ... |
17 июл. 2024 г. · The primary mechanism by which Amantadine Hydrochloride works is by modulating the activity of neurotransmitters in the brain, particularly dopamine. |
As an antiviral, it blocks the uncoating of influenza A virus preventing penetration of virus into host and inhibits M2 protein in the assembly of progeny ... |
Mechanism of Action: Antiviral. The mechanism by which amantadine exerts its antiviral activity is not clearly understood. It appears to mainly prevent the ... |
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