Atherosclerosis is initiated by endothelium activation and, followed by a cascade of events (accumulation of lipids, fibrous elements, and calcification), triggers the vessel narrowing and activation of inflammatory pathways.
This review focuses on the molecular mechanisms involved in the evolution of the atherosclerotic plaque that may pave the way for selecting optimal therapies. |
1 янв. 2005 г. · Atherosclerotic lesions develop as a result of inflammatory stimuli, subsequent release of various cytokines, proliferation of smooth muscle ... Abstract · Pathogenesis of Atherosclerosis |
5 дек. 2023 г. · Atherosclerosis can begin in childhood with the development of fatty streaks (table 1). The lesions of atherosclerosis advance with aging [3,4]. |
Endothelial cells, leukocytes, and intimal smooth muscle cells are the major players in the development of this disease. |
The article discusses different points of view on atherosclerosis development. The facts confirming the lipid hypothesis are presented. |
Endothelial cells, leukocytes, and intimal smooth muscle cells are the major players in the development of this disease. |
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