The development of cancer is an evolutionary process involving the sequential acquisition of genetic alterations that disrupt normal biological processes, ...

29 февр. 2024 г. · Our model unifies many previous molecular observations, providing a powerful new framework to investigate prostate cancer disease progression.

5 мар. 2024 г. · The researchers used AI to study changes in the DNA of prostate cancer samples (using whole genome sequencing) from 159 patients. They ...

27 нояб. 2017 г. · Prostate cancer diagnosis is routinely made by obtaining biopsy specimens under ultra-sound guidance. The Gleason score, assigned to the ...

3 янв. 2018 г. · This review surveys the enhanced landscape of genomic alterations in clinically localized and advanced prostate cancer.

The genomics of prostate cancer (PCA) has been difficult to study compared with some other cancer types for a multitude of reasons, despite significant ...

29 февр. 2024 г. · New research using AI has shown that prostate cancer includes two different subtypes of the disease, also known as evotypes.

10 янв. 2022 г. · We uncover heterogeneous cellular states in prostate epithelial cells marked by high androgen signaling states that are enriched in prostate cancer.

19 мая 2023 г. · Here, we review key updates in genetic and genomic testing for prostate cancer, including clinical implications of testing for advanced disease.

This review focuses on the clinical implications of prostate cancer genomics and the potential of cfDNA in facilitating treatment management.