The mode of action of cephalosporins is similar to that of the penicillins. Like the penicillins, cephalosporins bind to penicillin binding proteins and interfere with cell wall enzymes . Major adverse reactions to cephalosporins are also similar to those experienced with penicillin.
The cephalosporins are a class of β-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as Cephalosporium. Cephalosporin C · Cefepime · Cefotaxime · Cefazolin |
Cephalosporins inhibit peptidoglycan cross-linkage and therefore bacterial cell wall synthesis. Examples include cefazolin (first generation), cefoxitin (second ... |
Cephalosporins bind to the penicillin-binding proteins on bacteria and inhibit synthesis of the bacterial cell wall, causing cell lysis particularly in rapidly ... |
Cephalosporins are a diverse, extremely useful group of beta-lactam antibiotics employing a mechanism of action that requires bacterial replication for efficacy ... |
It inhibits the synthesis of the bacterial cell wall by inhibiting the enzymes (transpeptidases, carboxypeptidases) responsible for peptidoglycan synthesis, an ... |
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