Colchicine is poorly tolerated in the elderly and is best avoided. Intra-articular and systemic corticosteroids are increasingly being used for treating acute ...

Evidence suggests that colchicine, NSAIDs, and corticosteroids are all efficacious in the treatment of acute gout in the older adult.

12 февр. 2019 г. · For treatment of acute attacks in older people, dose reduction of colchicine may be needed due to renal impairment, and potential drug interactions require ...

31 янв. 2024 г. · However, elderly patients are more likely to have age-related kidney or liver problems which may require caution and an adjustment in the dose ...

Lower doses of colchicine are recommended for the elderly, for patients with hepatic or renal impairment, and for patients who weigh less than 50kg. *Stop when ...

14 нояб. 2022 г. · This is the first study revealing that colchicine usage is associated with better cognitive performance in older adults.

19 дек. 2017 г. · Among elderly patients, dosing is similar to that of other adults, and studies have found that it is not necessary to adjust the colchicine dose ...

Colchicine should be given with care in geriatric or debilitated patients and to those with cardiac, renal or gastrointestinal disease. The drug should be used.

Colchicine tablets combined with celecoxib capsules in the treatment of patients with gouty arthritis can reduce ESR, CRP and UA levels, improve the degree of ...

While NSAID use carries the risk of gastropathy, colchicine can cause diarrhea and other potentially serious side effects and should be avoided in patients who ...