1 апр. 2008 г. · The central pathological mechanism in macrovascular disease is the process of atherosclerosis, which leads to narrowing of arterial walls ...

The macrovascular complications of diabetes result from hyperglycemia, excess free fatty acid, and insulin resistance. These cause increased oxidative stress, ...

Pathological changes of major blood vessels leading to functional and structural abnormalities in diabetic vessels include endothelial dysfunction, reduced ...

9 дек. 2016 г. · Macrovascular disease develops in type 1 (T1DM) and type 2 diabetes mellitus (T2DM) and promotes the earlier and premature development of ...

Diabetes induces changes in the microvasculature, causing extracellular matrix protein synthesis, and capillary basement membrane thickening which are the ...

6 окт. 2023 г. · Elevated intracellular glucose in patients with diabetes leads to oxidative stress, which causes a rise in intracellular ROS, through trigger ...

Macro- and microvascular diabetic complications are mainly due to prolonged exposure to hyperglycemia clustering with other risk factors such as arterial ...

7 нояб. 2017 г. · Individuals with diabetes or prediabetes have a higher risk of developing myocardial infarction, stroke, and peripheral artery disease.

23 мар. 2023 г. · Complications from T2DM can be classified as microvascular complications, such as retinopathy, neuropathy and nephropathy, or macrovascular ... Introduction · Methods · Results · Discussion

10 апр. 2023 г. · Pathological changes of DR start with the loss of retinal neuronal. The series of events include early loss of neurovascular coupling, retinal ...