Diluents act as fillers in pharmaceutical tablets to increase weight and improve content uniformity. Natural diluents include starches, hydrolyzed starches, and partially pregelatinized starches. Common diluents include anhydrous lactose, lactose monohydrate, and sugar alcohols such as sorbitol, xylitol and mannitol .
Some diluents (such as microcrystalline cellulose) are often used as dry binders because they give the tablet high strength during the final compression. |
Lactose is widely used as an excipient in pharmaceutical manufacturing as a filler or diluent in tablets, capsules and to give bulk to powders (Figure 1). |
Diluents can include materials like lactose, mannitol, sorbitol, sucrose, and dextrose. The choice of a suitable diluent depends on factors such as the ... |
Common diluents include anhydrous lactose, lactose monohydrate, and sugar alcohols such as sorbitol, xylitol and mannitol. Diluents provide better tablet ... |
10 апр. 2024 г. · Commonly used diluents include microcrystalline cellulose (MCC), starch, mannitol, dibasic calcium phosphate, lactose, and sucrose. For instance ... |
For example, tetracycline formulas made with calcium phosphate as a diluent ... Due to the above feature, it is commonly used diluent in tablet formulation. |
Most commonly employed excipients ranked in ascending order of their brittleness are MCC, spray-dried lactose, β- lactose, α-lactose, α-lactose monohydrate, ... |
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