Diluents act as fillers in pharmaceutical tablets to increase weight and improve content uniformity . Natural diluents include starches, hydrolyzed starches, and partially pregelatinized starches. Common diluents include anhydrous lactose, lactose monohydrate, and sugar alcohols such as sorbitol, xylitol and mannitol.
23 окт. 2021 г. · Mannitol is used as a diluent (10 – 90% w/w) in tablet formulations. It's specific advantage is its low hygroscopicity and high compressibility. |
Some diluents (such as microcrystalline cellulose) are often used as dry binders because they give the tablet high strength during the final compression. |
10 апр. 2024 г. · Commonly used diluents include microcrystalline cellulose (MCC), starch, mannitol, dibasic calcium phosphate, lactose, and sucrose. For instance ... |
Diluents are chemically inactive excipients, mostly used to make up the required bulk of solid dosage form and used up to 80% in a formulation. |
Diluents act as fillers in pharmaceutical tablets to increase weight and improve content uniformity. Natural diluents include starches, hydrolyzed starches, ... |
Diluent adds bulk to make the tablet with practical size for compression and to be easily handledduring manufacture and to achieve targeted content. |
A diluent (also referred to as a filler, dilutant or thinner) is a diluting agent. Certain fluids are too viscous to be pumped easily or too dense to flow. |
Diluents are therefore used to formulate the tablets within the desired size range. • There are large numbers of diluents and the following are examples on them ... |
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