Bleeding following massive transfusion can occur due to hypothermia, dilutional coagulopathy, platelet dysfunction, fibrinolysis, or hypofibrinogenemia.

The transfusion of ten or more erythrocyte units (i.e. , replacement of one blood volume) within 24 h is generally considered as massive transfusion in adults.2 ... Effects of Hemodilution on... · Hemostasis Monitoring for...

Coagulopathy in trauma patients is a known contributor to death due to hemorrhage. In fact, it seen as frequently as 35% of the time.

Massive transfusion is a treatment for massive hemorrhage. It can keep patients alive through volume and oxygen transport replacement while other methods to ...

Coagulopathy associated with massive transfusion remains an important clinical problem. It is an intricate, multifactorial and multicellular event.

26 авг. 2005 г. · Coagulopathy associated with massive transfusion remains an important clinical problem. Treatment strategies must be adapted to the context and to the blood ... Abstract · Haemorrhage as a result of... · Conclusions

The management of dilutional coagulopathy due to fluid infusion and massive blood loss is a topic that deserves a biochemical approach.

The transfusion of ten or more erythrocyte units (i.e., replacement of one blood volume) within 24 h is generally considered as massive trans- fusion in adults.

Some of the complications of massive transfusion include: hypothermia; dilutional coagulopathy; hypocalcaemia, hypomagnesaemia, citrate toxicity; metabolic ...

In addition, thrombocytopenia is seen commonly in patients who have received massive blood transfusion, and has been thought to be a major cause of coagulopathy ...