Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene.

12 нояб. 2024 г. · This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain) ...

DMRT1 (Doublesex And Mab-3 Related Transcription Factor 1) is a Protein Coding gene. Diseases associated with DMRT1 include 46,Xy Sex Reversal 4 and Pituitary ...

12 нояб. 2024 г. · Data revealed that DMRT1 is a bifunctional transcriptional regulator, activating some genes and repressing others. Conditional gene targeting ...

DMRT1, a mammalian gene related to sex-determining genes in flies and nematodes, is located in a region of the human genome that is important for sex ...

Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation.

1 сент. 2021 г. · Dmrt1 is the only DMRT gene shown to play a conserved role in mammalian sexual differentiation. Dmrt1 is expressed specifically in the gonads of ...

DMRT1 encodes a male-specific transcriptional regulator with a conserved zinc finger-like DNA-binding domain, the DM domain, and is a key factor involved in ...

Dmrt1 is regarded as a conserved male-specific gene and plays a critical role in sex determination and sex differentiation in various species (Kopp, 2012). Sox9 ...

DMRT1 refers to a gene that is initially expressed in both somatic and germ cells of the bipotential gonad in mammals. While it is not involved in sex ...