15 июн. 2024 г. · It is generally recommended to slowly taper down your dose of Aricept before stopping completely. Your doctor can help you stop Aricept safely.

One published study has suggested that discontinuation of treatment with donepezil may bring withdrawal symptoms.

1 июн. 2018 г. · Abruptly stopping high-dose cholinesterase inhibitors is not recommended. Most clinical trials tapered these medications over 2 to 4 weeks.

Despite its long plasma-elimination half-life of 70 to 80 hours, a more gradual tapering from the 5-mg dose may be needed, rather than an abrupt ...

Tapering the dose may minimize the potential for withdrawal syndrome, including agitation, sleep disturbance, and mood changes. If symptoms worsen significantly ...

PP: The dose of the cholinesterase inhibitors and/or memantine should be tapered prior to discontinuation by halving the dose (or by stepping down through ...

Although recommencement on donepezil appears to reverse this deterioration we do not advise its abrupt discontinuation in this population. Copyright 2003 John ...

11 окт. 2021 г. · At end-of-life, it is typically recommended to reduce the dose of these medications by 25-50% every 1-2 weeks, although more gradual taper ...

A suitable tapering regimen may involve halving the dose every four weeks until the lowest strength of formulation is reached, then maintaining this dose for a ...