19 июл. 2022 г. · The results indicated that the introduction of metformin promoted an increase in bone thickness and area of reossification; the researchers ...

This meta-analysis indicated that metformin had no significant effect on BMD. Metformin decreased some bone turnover markers.

27 окт. 2023 г. · We can conclude that the use of metformin is a protective factor for osteoporosis and that the use of metformin has a causal relationship with osteoporosis.

Metformin treatment was associated with a higher T-score and a lower odds ratio of osteopenia and osteoporosis, especially in the female population, ...

10 янв. 2023 г. · A recent study also reported that metformin use was associated with a lower risk of osteoporosis/vertebral fracture in T2DM patients (37). A ...

26 нояб. 2019 г. · Metformin has a certain effect on microangiopathy and anti-inflammation, which can induce osteoporosis, activate the activity of osteoclasts, and inhibit ... Abstract · Introduction · Direct Effect of Metformin on...

Metformin, a widely used antidiabetic drug, has been shown to improve bone quality and decrease the risk of fractures in patients with diabetes.

27 мар. 2024 г. · This study indicated that metformin treatment is significantly associated with a reduction in the risk of OP, fracture and higher LS-BMD, FN-BMD, and eBMD.

In contrast, metformin and sulfonylureas do not appear to have a negative effect on bone health and may, in fact, protect against fragility fracture.