PP: The dose of the cholinesterase inhibitors and/or memantine should be tapered prior to discontinuation by halving the dose (or by stepping down through ... |
1 июн. 2018 г. · Abruptly stopping high-dose cholinesterase inhibitors is not recommended. Most clinical trials tapered these medications over 2 to 4 weeks. |
A suitable tapering regimen may involve halving the dose every four weeks until the lowest strength of formulation is reached, then maintaining this dose for a ... |
Tapering CHEIs Avoid abrupt discontinuation. If possible, taper by reducing the CHEI dose 25-50% every 1-2 weeks, to avoid withdrawal symptoms (9,11,12) ... |
11 окт. 2021 г. · At end-of-life, it is typically recommended to reduce the dose of these medications by 25-50% every 1-2 weeks, although more gradual taper ... |
Discontinuing Dementia Medications - Enclara Pharmacia Case enclarapharmacia.com › Palliative Pearls
Taper the drug by decreasing the dose by half for two weeks and then stop. Assess for any reappearance of behavioral or psychological symptoms. If they recur, ... |
Reduce to half dose for two weeks · GP review at two weeks · Discontinue immediately after a further two weeks · Review again after one week. |
In Herrmann 2016, participants in the discontinuation group were tapered off their baseline dose of ChEI (donepezil, galantamine or rivastigmine) for two weeks ... |
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