Donepezil, an acetylcholinesterase inhibitor currently indicated for use in patients with mild to moderate AD, has recently been evaluated in VaD.

Conclusions: Donepezil-treated patients demonstrated significant improvements in cognition and global function compared with placebo-treated patients, and ...

In our study, donepezil-treated patients with probable or possible VaD demonstrated significant improvement on the ADAS-cog and the MMSE, relative to placebo, ...

22 февр. 2021 г. · People taking donepezil or galantamine had better scores on memory and thinking tests than people taking placebo, but the benefits were modest ...

11 сент. 2003 г. · These data demonstrate that donepezil is an effective and well-tolerated treatment for VaD and show it may have an important place in the management of this ...

In patients with vascular dementia, treatment with donepezil produces small, but not clinically significant, changes in cognitive function.

1 мая 1999 г. · We report on our preliminary clinical experience of the effects of donepezil on the cognitive and behavioral symptoms of patients with VaD.

8 янв. 2020 г. · Donepezil is used to treat mild to moderate AD, and it has been shown to treat cognitive impairment and memory deficits caused by VD.

20 нояб. 2003 г. · These results suggest that donepezil has some efficacy in patients with vascular dementia, but the benefits were modest compared with placebo ...

Background and Purpose—Clinical observations suggest that patients with vascular dementia (VaD) may benefit from treatment with cholinesterase inhibitors.