31 окт. 2019 г. · However, neither of these dual combinations is sufficiently effective in persons with cystic fibrosis who have a single Phe508del allele and a ...

Elexacaftor-tezacaftor-ivacaftor was efficacious in patients with cystic fibrosis with Phe508del-minimal function genotypes, in whom previous CFTR modulator ...

7 нояб. 2019 г. · 9,11 However, neither of these dual combinations is sufficiently effective in persons with cystic fibrosis who have a single Phe508del allele ...

22 окт. 2024 г. · Conclusions: Elexacaftor-tezacaftor-ivacaftor was efficacious in patients with cystic fibrosis with Phe508del-minimal function genotypes, in ...

Elexacaftor-tezacaft or-ivacaft or was efficacious in patients with cystic fibrosis with Phe508del-minimal function genotypes, in whom previous CFTR ...

18 янв. 2024 г. · ELX-TEZ-IVA demonstrated efficacy in improving ppFEV1, CFQ-R RD, and sweat chloride concentrations in patients with CF.

Study: Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele. Authors: P.G. Middleton, M.A. Mall, P. Dřevínek, L.C. Lands, ...

18 янв. 2024 г. · ELX-TEZ-IVA has been approved for patients aged 12 years and older who carry at least one Phe508del mutation in the CFTR gene, which accounts ...

6 февр. 2020 г. · The efficacy of elexacaftor-tezacaftor-ivacaftor was confirmed in this trial in patients 12 years or older who were heterozygous for the ...

7 нояб. 2019 г. · Elexacaftor-tezacaftor-ivacaftor was efficacious in patients with cystic fibrosis with Phe508del-minimal function genotypes, in whom previous CFTR modulator ...