Hypofibrinogenemia is an important cause of bleeding in trauma patients. The treatment remains fibrinogen replacement with cryoprecipitate or fibrinogen ...

14 янв. 2020 г. · Fibrinogen plays an important role in haemostasis during the early phase of trauma, and low fibrinogen levels after severe trauma are ...

A high fibrinogen count exerts a protective effect with regard to the amount of blood loss. In multiple trauma patients, priority must be given to early and ...

25 янв. 2023 г. · Low fibrinogen (ie, <100 mg/dL) is associated with mortality and increased blood product transfusion in severely injured trauma patients; ...

20 янв. 2017 г. · In severe trauma patients, plasma fibrinogen concentrations decrease earlier and more frequently than other coagulation factors, predicting massive bleeding ...

Summary. Background: Low fibrinogen levels are known to occur in trauma. However, the extent of fibrinogen depletion during trauma hemorrhage, the response ...

Background. Decreased plasma fibrinogen concentration shortly after injury is associated with higher blood transfusion needs and mortality.

Fibrinogen level is decreased in injured patients on admission and is associated with poor outcomes. ROTEM is a rapid means of assessing hypofibrinogenemia.

Fibrinogen is the first coagulation factor to decrease after massive hemorrhage. European massive transfusion guidelines recommend early repletion of fibrinogen ...