Conclusion The strongest risk factors for treatment failure in GCA are treatment with prednisone alone and female sex. Lower starting prednisone doses and ...

Failure of response of giant cell arteritis (GCA) to corticosteroid therapy has invariably been attributed to the delay in diagnosing the disease or the use ...

Bone protection: The treatment of GCA requires both long-term and high dose glucocorticoid therapy. Oral glucocorticoid treatment with the equivalent of > 5 mg ...

1 авг. 2024 г. · The occasional patient with GCA who does not respond adequately to steroid therapy requires a referral for reconsideration of the diagnosis and ...

28 апр. 2021 г. · Although patients with GCA respond very well to high-dose glucocorticoids, between 34-75% of patients will experience a relapse during their ...

9 нояб. 2022 г. · However, not all patients tolerate or respond adequately to corticosteroids, and prolonged dosages increase the risk for adverse side effects.

Methotrexate, azathioprine, and cyclophosphamide have been used in rare patients who do not respond to adequate prednisone. Long–term follow–up is required ...

We recommend tapering prednisone only after disease control has been achieved, that is, after the ESR and CRP have normalized and when systemic symptoms of GCA ...

23 февр. 2018 г. · We discuss the safety issues associated with long-term glucocorticoid use in patients with GCA and strategies for preventing glucocorticoid-related morbidity.

10 нояб. 2022 г. · If your GCA doesn't respond well to prednisone, or if you are needing high doses, you may be referred to a rheumatologist to consider other ...