The human GeCKO (Genome-Scale CRISPR Knockout) lentiviral pooled libraries target early consecutive exons for genome editing.

First, we used the GeCKO library to identify genes essential for cell viability in cancer and pluripotent stem cells. Next, in a melanoma model, we screened for ...

For genome editing in the gecko (Fig. 1A), we sought to adapt the CRISPR/Cas9-mediated genome editing method previously described in Anolis lizard (Rasys ...

1 мар. 2023 г. · We report the development of a related method for genome editing in the Madagascar ground gecko (Paroedura picta), a well-established experimental model.

640,00 $ The mouse GeCKO (Genome-Scale CRISPR Knock-Out) lentiviral pooled libraries target early consecutive exons for genome editing.

999,00 $ The genome-wide GeCKO and SAM libraries were designed to target every gene in the mouse or human genes and knock-out or transcriptionally activate each gene, ...

Here we describe how to amplify GeCKO v2.0 DNA plasmids to have sufficient quantity to produce lentivirus, while maintaining full library representation.

Agilent's GeCKO CRISPR catalog libraries are available in three formats; ready to package, ready to clone, and ready to amplify. All ...

We show that lentiviral delivery of a genome-scale CRISPR-Cas9 knockout (GeCKO) library targeting 18,080 genes with 64,751 unique guide sequences enables ...

4 авг. 2024 г. · ... CRISPR-Cas9 knockout (GeCKO) library to probe 18,080 genes in the human. genome for roles in BRAF-inhibitor vemurafenib resistance in a ...