Resistance mechanisms have probably evolved from genes present in organisms producing antibiotics ... The final mechanism by which bacteria may protect ...

14 окт. 2021 г. · The origin and molecular basis of bacterial resistance is the presence of antibiotic resistance genes (ARGs).

1 окт. 2016 г. · From an evolutionary perspective, bacteria use two major genetic strategies to adapt to the antibiotic “attack”, i) mutations in gene(s) often ...

Antibiotic resistance genes are likened to non-static genetic elements, which can be easily exchanged between different species of microbes via horizontal gene ...

15 мар. 2021 г. · The most prevalent resistance genes among K. pneumoniae and K. quasipneumoniae isolates were fosA (100%), blaSHV (97.8%), and oqxAB (97.8%, ...

by Szybalski and Bryson (28). In clinical application of drugs, however, other factors than resistance may play a role in the survival of bacteria.

The main mechanisms of gene variation leading to variation and diversification of antibiotic-resistance genes are mutation, recombination, and amplification.

26 мая 2023 г. · This review will focus on plasmid-mediated bacterial genes, especially those that encode ESBLs, and how they contribute to antibiotic resistance.

Genetic resistance of microbes to antibiotics is due to a chromosomal mutation in the bacterial DNA or acquisition of antibiotic resistance genes on plasmids.

This raises the possibility that compounds other than antibiotics could select for maintenance of antibiotic resistance genes in the same bacterium.