10 февр. 2022 г. · This Primer describes the basic and advanced concepts of CRISPR screening and its application as a flexible and reliable method for biological discovery.

CRISPR screens are a powerful source of biological discovery, enabling the unbiased interrogation of gene function in a wide range of applications and species.

High-content screens have the potential to become the primary method of CRISPR screening as they allow simultaneous screening and initial phenotyping of cells.

This review details recent methodological advances in high-content CRISPR screens and highlights the impact this technology is having on tumor immunology.

This review details recent methodological advances in high-content CRISPR screens and highlights the impact this technology is having on tumor immunology.

25 мар. 2024 г. · Pooled CRISPR screening based on image information has great potential to map complex genotype-phenotype associations in mammalian cells.

24 окт. 2023 г. · In this review, we discuss the use of bulk CRISPR screening in hematology research, as well as the emergence of single-cell CRISPR screening and its added ...

We offer customized screening plates from a genome wide single guide RNA (sgRNA) CRISPR library. Several human siRNA libraries are readily available, ...

CRISPR screens are a powerful source of biological discovery, enabling the unbiased interrogation of gene function in a wide range of applications and species.

This Primer describes the basic and advanced concepts of CRISPR screening and its application as a flexible and reliable method for biological discovery.