The Lord God of hosts has a day of tumult and trampling and confusion in the valley of vision, a battering down of walls and a cry for help to the mountains.

I will place on his shoulder the key of the house of David; he shall open, and no one shall shut; he shall shut, and no one shall open.

22 And I will place on his shoulder the key of the house of David. He shall open, and none shall shut; and he shall shut, and none shall open.

Chapter 22 is an oracle against the city of Jerusalem. Isaiah condemns the people for celebrating instead of mourning and seeking the Lord's help.

I will thrust you from your office, and you will be pulled down from your post. On that day I will call my servant Eliakim son of Hilkiah,...

וּמִקְוָ֣ה ׀ עֲשִׂיתֶ֗ם בֵּ֚ין הַחֹ֣מֹתַ֔יִם לְמֵ֖י הַבְּרֵכָ֣ה הַיְשָׁנָ֑ה וְלֹ֤א הִבַּטְתֶּם֙ אֶל־עֹשֶׂ֔יהָ וְיֹצְרָ֥הּ מֵרָח֖וֹק לֹ֥א רְאִיתֶֽם׃ and you constructed a basin between the two walls for the water of the old pool ...

This is a time of panic, defeat, and confusion in the Valley of Vision, and the Sovereign LORD Almighty has sent it on us.

Isaiah 22:22 I will place on his shoulder the key to the house of David; what he opens no one can shut, and what he shuts no one can open.

Isaiah saw an army full of arrows and chariots coming against Jerusalem. He prophesied the attack and overthrow of Jerusalem by the Babylonians.

Chapter 22. Jerusalem will be attacked and scourged—The people will be carried captive—The Messiah will hold the key of the house of David, inherit glory, ...