Genetic variants and autoantibodies, or a combination of both, may prove useful to generate predictors of clinical phenotypes or disease course in juvenile ...

There is likely to be a genetic (hereditary) predisposition to all autoimmune diseases and children who have JDM may have a relative who suffers from another ...

Genetic factors are likely important in the pathogenesis of JDM. These include several Human Leukocyte Antigen alleles, in particular those associated with the ...

27 сент. 2024 г. · At present, no single genetic changes have been identified that condition the onset of JDM, although it is believed that the combination of ...

23 окт. 2024 г. · Type I interferon-alpha/beta genes are overexpressed in dermatomyositis. Gene expression profiles of untreated patients may provide ...

This is more likely to happen in certain people based on their genetics. It is very rare for other family members to develop JDM and JDM is not contagious.

23 апр. 2021 г. · The purpose of this study was to identify key genes related to JDM. Microarray datasets were downloaded from the Gene Expression Omnibus ...

Genes causing the potential monogenic subset of cases in this condition have not yet been described with sufficient evidence for 'green' status in PanelApp.

Association with HLA-DRβ1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis | Human Molecular Genetics | Oxford Academic.

Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. Arthritis Rheum. 2013, 65, 3239–3247. [Google ...