Kinetic solubility testing is used to evaluate the solubility of a compound that is already fully dissolved in an organic solvent, typically DMSO. A small ...

27 дек. 2023 г. · Kinetic aqueous or buffer solubility is important parameter measuring suitability of compounds for high throughput assays in early drug ... Introduction · Data · Method · Results and discussion

15 мая 2018 г. · Kinetic solubility offers a high-throughput method with relatively small amount of compound, especially useful in the early discovery phases.

Kinetic solubility measurements using prototypical assay buffer conditions are presented for a ~58000 member library of small molecules.

Kinetic solubility is the intrinsic molecular solubility that can be improved by changing the chemical structure; some cases, it is an upper limit, however, ...

Kinetic aqueous or buffer solubility is important parameter measuring suitability of compounds for high throughput assays in early drug discovery while ...

29 апр. 2014 г. · This review will provide an understanding of the distinction between thermodynamic and kinetic solubility, and how one can exceed the equilibrium solubility to ...

Kinetic solubility measures a precipitation rate rather than solubility. Kinetic solubility methods are designed to facilitate high throughput measurements, ...

Kinetic solubility is measured with a high throughput assay using a stock solution of compound already dissolved in an organic solvent (typically DMSO). This ...