21 нояб. 2022 г. · Patients treated with lansoprazole had a 44% lower risk of osteoporosis than the comparison cohort who underwent other PPI therapy.

19 февр. 2022 г. · Longterm administration of LPZ induced osteoporotic symptoms in mice, and LPZ triggered calcium increases in osteoblasts in a concentration-dependent manner.

10 авг. 2024 г. · Results: Patients receiving lansoprazole treatment had a reduced risk of osteoporosis as compared with those undergoing other PPI therapy ( ...

Recent studies have revealed that lansoprazole administration led to decreased BMD and impaired bone microarchitecture in mice, inducing OBs apoptosis on ...

The manuscript by Ming-Hsuan Chung et al claimed and concluded that proton pump inhibitor (PPI) lansoprazole treatment had a reduced osteoporosis risk as ...

5 авг. 2020 г. · A systematic review suggests a modest increase in the risk of hip fracture and vertebral fracture associated with PPIs, although some studies showed ...

A growing body of evidence suggests a correlation between prolonged PPI use and an increased risk of bone fractures.

16 мая 2018 г. · Some patients on certain types of medication are at a higher risk of developing osteoporosis, with the medication having negative effects on bone health.

The Bottom Line. Long-term use of proton pump inhibitors (PPIs) is not associated with changes in bone structure and strength that lead to fracture.

Many systematic reviews and observational studies have shown an increased risk of osteoporotic fractures after the long-term use of PPIs (Zhou et al., 2016; ...