The cellular and molecular genetic changes underlying lung cancer have become better understood over the past 25 years, but the stepwise progression of ...

Lung cancer pathogenesis is also affected by a genetic component: it relates to the host susceptibility to lung cancer, with or without exposure to carcinogens.

The pathogenesis of lung cancer is initiated either by the activation of oncogenes or the inactivation of tumor suppressor genes.

Of lung cancers, 85% are caused by tobacco smoke, which induces a stepwise accumulation of genetic and epigenetic abnormalities leading to pre-invasive lesion ... CAUSES (AETIOLOGY) OF... · ABNORMALITIES IN...

Lung cancer is the end stage of multiple-step carcinogenesis, in most cases driven by genetic and epigenetic damage caused by chronic exposure to tobacco smoke ...

Findings suggest that lung cancer develops through a stepwise process from normal lung epithelial cells towards frank malignancy.

This review summarizes the state of knowledge of human lung cancer pathogenesis and the molecular pathology of premalignant lung lesions.

We focus on how studying lung adenocarcinomas at a cell-by-cell level continues to unravel an unbeknownst level of intratumor heterogeneity.

14 июн. 2012 г. · In this review, the molecular abnormalities associated to the early pathogenesis of the two most common histological types of lung cancer, SCC ...

27 дек. 2012 г. · The pathogenesis of lung cancer is like other cancers, beginning with carcinogen-induced initiation events, followed by a long period of promotion and ...