Most commonly, M1 macrophages are positively associated with longer survival times and most positive clinical outcomes in many cancers such as small cell lung cancer [79], non-small cell lung cancer [80], colorectal cancer [81], ovarian cancer [77], breast cancer [82], oral squamous cell carcinoma [83], and more.
2 дек. 2020 г. · M1-type macrophages have anti-tumor effects, which can distinguish tumor cells from normal cells. By identifying tumor cells and ultimately ... |
21 июл. 2021 г. · M1 phenotype macrophages are tumor-resistant due to intrinsic phagocytosis and enhanced antitumor inflammatory reactions. Contrastingly, M2 are ... |
M1 macrophages are involved in immune activation, promoting apoptosis and phagocytosis of cancer cells. M2 macrophages were mainly activated by IL-4 and mainly ... |
M1-type macrophages are capable of inducing lysis in various types of cancer cells, but the mechanism of action is unclear. |
The role of M1-like macrophages in the TME is mainly pro-inflammatory and they inhibit tumor progression. Most studies have focused on M2-like macrophages, ... |
22 мар. 2022 г. · Our results demonstrate that M1 macrophages induce the proliferation, migration, invasion, and xenograft development of OSCC cells. Introduction · Results · Discussion · Materials and Methods |
M1 macrophages exert anti-tumor effects, mediating phagocytosis and antibody-dependent cell-mediated cytotoxicity to kill tumor cells. M1 polarization is ... |
8 апр. 2024 г. · Therefore, M1 macrophages polarized by APW-CP showed anti-tumor activity against the breast cancer cells and β-glucan may be the potential M1- ... |
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