The mechanism of action of macrolides is inhibition of bacterial protein biosynthesis by preventing peptidyl transferase from adding the growing peptide attached to tRNA to the next amino acid (similarly to chloramphenicol) 121 as well as inhibiting ribosomal translation.
Interactions. CYP3A4 is an enzyme that metabolizes many drugs in the liver. Macrolides inhibit CYP3A4, which means they reduce its activity and increase the ... Erythromycin · Clarithromycin · Lactone |
Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome. They bind at the nascent peptide exit tunnel and partially occlude it. |
Macrolides' mode of action is bacteriostatic (inhibit the growth of bacteria), whereas, at higher concentrations, they are bactericidal (kill the bacteria). What Are Macrolides? · Macrolide Antibiotics |
![macrolides [TUSOM | Pharmwiki]](imgx.php?https://tmedweb.tulane.edu/pharmwiki/lib/exe/fetch.php/amg.png)
Macrolides are antibiotics that are primarily bacteriostatic; by binding to the 50S subunit of the ribosome, they inhibit bacterial protein synthesis. |
The general mode of action of macrolide antibiotics is through inhibiting protein assembly by reversible binding to the large 50S subunit of the bacterial. |
The mechanism of action of macrolides has been studied for more than 30 years but is still unclear. All macrolides inhibit bacterial protein synthesis to ... |
Macrolides are mainly bacteriostatic, and bind to the 50S ribosomal subunit that inhibits the synthesis of bacterial protein. They also have anti-inflammatory ... |
| Novbeti > |
| Axtarisha Qayit Anarim.Az Anarim.Az Sayt Rehberliyi ile Elaqe Saytdan Istifade Qaydalari Anarim.Az 2004-2023 |