2 мая 2020 г. · The mechanisms of MDR include elevated metabolism of xenobiotics, enhanced efflux of drugs, growth factors, increased DNA repair capacity, and ...

The mechanisms of MDR include elevated metabolism of xenobiotics, enhanced efflux of drugs, growth factors, increased DNA repair capacity, and genetic factors ( ...

Resistance exists against every effective anticancer drug and can develop by numerous mechanisms including decreased drug uptake, increased drug efflux, ...

28 авг. 2023 г. · The mechanisms underlying MDR include ATP-binding cassette (ABC) transporter overexpression, autophagy, DNA damage repair, cancer stem cells, ...

Resistance exists against every effective anticancer drug and can develop by numerous mechanisms including decreased drug uptake, increased drug efflux, ... Не найдено: chemotherapy | Нужно включить: chemotherapy

Numerous mechanisms contribute to tumor cells' drug resistance, such as the development of multidrug resistance (MDR) after prolonged chemotherapy, improved DNA ...

MDR cell lines are resistant to the so-called naturally occurring anti-cancer drugs, such as anthracyclines, Vinca alkaloids and epipodophyllotoxins.

Growing evidence suggests that MDR is mediated by the increased efflux of chemotherapeutic drugs, which reduces the drug absorption by cancer cells (32). The ...

9 июл. 2008 г. · Principal mechanisms may include altered membrane transport involving the P-glycoprotein product of the multidrug resistance (MDR) gene as well as other ...

1 февр. 2002 г. · Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell ...