23 авг. 2022 г. · Metformin may be beneficial in the treatment of osteoarthritis by inhibiting inflammation, modulating autophagy, antagonizing oxidative stress, and reducing ...

7 мар. 2023 г. · The results of our study demonstrated significant beneficial effects of metformin on the general conditions of OA patients. Metformin also ...

20 мар. 2023 г. · In the adjusted analysis, the risk of developing OA was reduced by 24% for individuals treated with metformin compared with a sulfonylurea (aHR, ...

There is evidence emerging from pre-clinical and human studies suggesting metformin may have disease-modifying properties in osteoarthritis7, 8, 9, 10, 11.

The present study suggests that metformin, administered shortly after joint injury, can limit OA development and progression in injury-induced OA animal models.

22 февр. 2020 г. · Metformin attenuates osteoarthritis structural worsening and modulates pain, suggesting its potential for osteoarthritis prevention or treatment ...

13 июн. 2024 г. · Metformin as an adjuvant therapy in obese knee OA patients may have beneficial effects on cartilage degradation and inflammation, as evidenced ...

21 мар. 2023 г. · Use of the first-line type 2 diabetes drug metformin was associated with a lower incidence of osteoarthritis, according to a new study.

24 авг. 2022 г. · Recent evidence has suggested that metformin — as an AMPK activator — is a potential disease-modifying agent for OA.