19 июл. 2022 г. · This study demonstrates that Met improved bone density and reduced the effects of T2DM on adiposity formation in the animal models.

In summary, there is no negative effect on BMD for patients treated with metformin, although no protective effect is discovered. PINP and CTX are decreased by ...

10 янв. 2023 г. · A recent study also reported that metformin use was associated with a lower risk of osteoporosis/vertebral fracture in T2DM patients (37). A ...

27 мар. 2024 г. · This study indicated that metformin treatment is significantly associated with a reduction in the risk of OP, fracture and higher LS-BMD, FN-BMD ...

27 окт. 2023 г. · We can conclude that the use of metformin is a protective factor for osteoporosis and that the use of metformin has a causal relationship with osteoporosis.

Conclusions. Metformin treatment was associated with a higher T-score and a lower odds ratio of osteopenia and osteoporosis, especially in the female population ...

Metformin, a widely used antidiabetic drug, has been shown to improve bone quality and decrease the risk of fractures in patients with diabetes.

16 авг. 2023 г. · In this study, we observed that metformin increased the expansion of type H vessels throughout osteoporotic as well as normal fracture repair, ...

25 окт. 2022 г. · In this study, we demonstrated for the first time that metformin administration alleviated bone loss in postmenopausal women and ovariectomized mice.