7 июл. 2022 г. · Metformin has been shown to modulate meta-inflammation, an important pathogenesis in knee osteoarthritis (OA). The study aimed to test the ...

8 дек. 2023 г. · Hence, metformin has the potential to reduce pain in those with knee OA and overweight or obesity. This study aims to determine the effect of ...

We concluded that metformin may be beneficial in the treatment of osteoarthritis by inhibiting inflammation, modulating autophagy, antagonizing oxidative ... Mechanism of metformin... · Beneficial evidence for the...

21 мая 2022 г. · Animal experiments and observational studies have suggested that metformin may have protective effects on knee OA.

7 мар. 2023 г. · Our findings support the possible beneficial effects of metformin on improving pain, ADL, Sport/Rec, and QOL in OA patients. Our findings ...

19 сент. 2022 г. · Patients with type 2 diabetes who report regular metformin use demonstrate a potential slowing of knee OA progression, according to data derived ...

13 июн. 2024 г. · Metformin as an adjuvant therapy in obese knee OA patients may have beneficial effects on cartilage degradation and inflammation, as evidenced ...

The present study suggests that metformin, administered shortly after joint injury, can limit OA development and progression in injury-induced OA animal models.

26 окт. 2024 г. · Post-treatment results showed a statistically and clinically significant improvement in pain intensity, knee ROM, and function in the MFPH group.

26 июл. 2023 г. · The result showed that the diabetes patients who took metformin had lower odds of having musculoskeletal pain in the back, knee, and should/neck ...