Pathophysiology of osteoarthritis. Osteoarthritis (OA) is an idiopathic disease character- ized by a degeneration of articular cartilage. A breakdown of the ...

22 окт. 2024 г. · In the present review, we described the most important risk factors and morphological changes in the cartilage and bone during the development of OA.

Hallmarks of OA such as synovial membrane inflammation, cartilage degeneration with the release of danger-associate molecular patterns (DAMPs), osteochondral ...

Osteoarthritis (OA) is characterized by a degeneration of articular cartilage, in which the breakdown leads to matrix fibrillation, fissure appearance, gross ...

The pathological changes include articular cartilage degradation, and synovitis beside alteration in periarticular tissues, menisci and ligaments degeneration.

12 окт. 2022 г. · Indeed, modern imaging approaches have shown that OA pathogenesis involves the breakdown of cartilage and structural changes in the whole joint ...

Degradation of the cartilage extracellular matrix (ECM) is appreciated to be an impor- tant feature of OA pathogenesis that, together with bone remodeling, ...

30 июл. 2006 г. · The characteristic structural changes in OA include the progressive loss of articular cartilage, increased subchondral plate thickness, ...

Osteoarthritis (OA) is characterized by a degeneration of articular cartilage, in which the breakdown leads to matrix fibrillation, fissure appearance, gross ...

It results from inflammation and abnormal friction between the joint surfaces, and it is one of the warning bells that leads the physician to a diagnosis [29].