1 сент. 2023 г. · PAX8 is comprised of an N terminal DNA binding domain, an octapeptide and a C terminal DNA binding domain.

3 июн. 2024 г. · Abundant tumor associated lymphocytes are present. The tumor cells are positive for CK7 and PAX8 with abnormal (overexpression) of p53 but ...

PAX8 is expressed at high levels in specific types of tumor, including thyroid and renal carcinomas and pancreatic neuroendocrine tumors.

25 июн. 2024 г. · Most common renal epithelial tumor, accounting for ~2% of all malignancies, typically with clear cytoplasm and a compact nested or acinar growth pattern.

25 сент. 2024 г. · PAX8, CAIX and TFE3 expression panel will be helpful to confirm and classify renal cell carcinoma. MelanA, inhibin and calretinin are expressed ...

2 окт. 2024 г. · The endometrioid carcinoma component is positive for PAX8, ER and PR and is negative for napsin A and WT1. Both components show loss of MLH1 and ...

8 авг. 2018 г. · The role of PAX8 during embryogenesis may provide a clue as to why renal cell carcinomas may metastasize to the thyroid gland. Nuclear ...

Expression of PAX8 (PAX-8) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.

PAX8 is a paired-box gene important in embryogenesis of the thyroid, Müllerian, and renal/upper urinary tracts, and expression of PAX8 has been previously ...

25 сент. 2024 г. · The images show a clear cell adenocarcinoma, which should have positive staining for PAX8, CK7 and a p53 mutated phenotype. Vimentin should be ...