PDGFRA is an inclusion criterion in 25 clinical trials for malignant solid tumor, of which 20 are open and 5 are closed. Of the trials that contain PDGFRA ...

13 июл. 2021 г. · Genetic abnormalities that involve the PDGFRA gene cause a type of blood cell cancer called PDGFRA-associated chronic eosinophilic leukemia.

Platelet-derived growth factor receptor A (PDGFRA) mutations occur in approximately 10–15% of gastrointestinal stromal tumors (GISTs).

A gene that makes a protein that is involved in cell division and cell survival. Mutated (changed) forms of the PDGFRA gene and protein have been found in some ...

10 июн. 2013 г. · Ten novel somatic point mutations in PDGFRA have been reported in a variety of cancers, namely isolated cases of glioblastoma, melanoma, acute ...

6 дней назад · Microarray data of the expression level of key genes reveals that PDGFRA is critical for cervical cancer invasion and metastasis. plays a ...

PDGFRA Mutation is an inclusion criterion in 2 clinical trials for small cell lung carcinoma, of which 2 are open and 0 are closed. Of the trials that contain ...

This study will concentrate on the regulation of the PDGF/PDGFR signaling system, in particular the current methods and inhibitors used in cancer treatment.

PDGFRA Hallmarks of Cancer. Explore the role of PDGFRA in cancer within the context of the hallmarks behaviours and functional descriptions.

19 нояб. 2020 г. · PDGFRα showed a crucial role in therapy resistance given its impact in both stromal and tumor cells which intensify tumor proliferation. In this ...