Resistance to penicillins is most often due to the production of β-lactamases that hydrolyse the β-lactam ring (see Fig. 51.3). There are hundreds of β-lactamases, many of which are closely related to penicillin-binding proteins, but some are structurally different metalloenzymes.
The molecular basis of penicillin resistance is mutation in the bacterial genes encoding for high-molecular-weight penicillin-binding proteins. |
| Антибиотикорезистентность |  |
Устойчивость к противомикробным препаратам возникает, когда микробы развивают механизмы, которые защищают их от воздействия противомикробных препаратов. Антибио́тикорезисте́нтность — это частный случай устойчивости к противомикробным препаратам,... Википедия
29 мар. 2017 г. · The spread of penicillin resistance was already documented by 1942, when four Staphylococcus aureus strains were found to resist the action of ... |
The antibiotic resistance crisis has been attributed to the overuse and misuse of these medications, as well as a lack of new drug development by the ... |
Bacteria Can Become Resistant to Penicillin by Modifying Enzymes That Make the Cell Wall. Some bacteria, including Streptococcus phenominae, have developed ... |
21 нояб. 2023 г. · Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial medicines. As a result of ... |
“It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same ... |
Find out about antibiotic (antimicrobial) resistance and why antibiotics are no longer prescribed to treat certain infections. |
Antibiotic resistance is when bacteria change so antibiotic medicines can't kill them or stop their growth. As a result, bacterial infections are difficult ... |
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