7 дек. 2023 г. · Epileptic patients on phenytoin therapy that were 18–55 years old exhibited higher associated risk of osteoporosis and osteoporotic-fragility fractures of ...

Conclusion: Epileptic patients on phenytoin therapy that were 18-55 years old exhibited higher associated risk of osteoporosis and osteoporotic-fragility ...

1 нояб. 2015 г. · We present an unusual case that uniquely highlights both adverse effects of phenytoin on bone metabolism and side effects of its overtreatment.

11 дек. 2014 г. · Data suggests that long-term use of carbamazepine, phenytoin, primidone, and sodium valproate is associated with decreased bone mineral density.

23 июл. 2009 г. · Previous studies have made references to prolonged treatment with phenytoin as a possible risk factor in the development of osteoporosis ...

phenytoin; primidone; long-term treatment with sodium valproate. can reduce bone density which may lead to osteoporosis and broken in certain 'risk' groups.

1 мар. 2011 г. · Chronic administration of phenytoin (PHT) has been associated with bone loss. Bisphosphonates [alendronate (ALD), ibandronate (IBD) and ...

Phenytoin treatment of osteoblast-like cells with a clinically relevant dose results in a reduction of pro-collagen I protein.

26 июн. 2008 г. · Phenytoin monotherapy was associated with lower femoral neck BMD. Antiepileptic drugs (AEDs) have adverse effects on bone health, but ...

1 нояб. 2017 г. · Previous studies have demonstrated that treatment with phenytoin decreased bone mineral density (BMD) owing to enhanced bone resorption.