In particular, dorsomedial thalamic nuclei, periaqueductal grey matter and caudate hyperintensity are seen. Occasionally parieto‐occipital white matter and ...

11 июл. 2024 г. · Prion diseases, also known as transmissible spongiform encephalopathies, are caused by the accumulation of dysmorphic proteins named prions.

A brain MRI suggestive of sCJD demonstrates hyperintensity in the caudate and putamen, and/or at least two cortical regions (temporal, parietal, occipital).

9 июл. 2024 г. · On imaging, it classically manifests as hyperintense signal on DWI (and usually FLAIR) in regions of the cerebral grey matter (cortex, followed by the striatum ...

5 дек. 2012 г. · The original criteria include dementia with variety of neurological signs, the presence of 14.3.3 proteins in the CSF and characteristic EEG ...

1 июн. 2020 г. · The findings suggest that diffusion MRI is an accurate test for establishing a diagnosis of prion diseases in the appropriate clinical context.

12 апр. 2012 г. · The main imaging finding in CJD is abnormal signal within the cortex and/or the striatum, and to a lesser extent, the thalamus (Figs. 1-4). No ...

Images typically show abnormal signal on DWI sequences in the cortex, putamen and head of the caudate nucleus; but unusual patterns can also occur. Sensitivity ...

27 июл. 2020 г. · MRI is considered the most sensitive technique for the detection of CJD-related abnormalities in vivo.

Herein, we present a review of the neuroi- maging features of the prion disorders known to affect humans emphasizing the important contribution of MRI in the ...