Scaffold proteins selectively bring together specific proteins within a signaling pathway and provide selective spatial orientation and temporal coordination to ... |
20 окт. 2022 г. · Scaffold proteins act as molecular hubs for the docking of multiple proteins to organize efficient functional units for signaling cascades. |
Key Takeaways · Scaffold proteins facilitate precise spatial arrangement, shielding signaling pathways from deactivation, and boosting signaling efficiency. |
7 авг. 2023 г. · We identify 24 proteins with conserved EV-sorting abilities across five types of producer cells. TSPAN2 and TSPAN3 emerge as lead candidates and outperform the ... |
7 сент. 2010 г. · Scaffold/anchor proteins usually bind more than two signaling components together and regulate their activity in complex and dynamic ways, ... Abstract · Introduction · Scaffold/anchoring proteins |
21 июл. 2022 г. · We describe deep learning approaches for scaffolding such functional sites without needing to prespecify the fold or secondary structure of the scaffold. |
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