| Scaffold protein |  |
В биологии каркасные белки являются важными регуляторами многих ключевых сигнальных путей. Хотя функции каркасов строго не определены, известно, что они взаимодействуют и/или связываются с множественными членами сигнального пути, связывая их в... Википедия (Английский язык)
Examples of scaffold proteins include those that control the MAPK system that phosphorylates different target proteins and proteins that regulate the opening ... |
24 янв. 2024 г. · Among them, nPIST and RIL are regarded as scaffold proteins. nPIST binds to NMDA receptor subunit 2A by a PDZ domain and to stargazin by a ... |
Scaffold Protein - an overview | ScienceDirect Topics www.sciencedirect.com › medicine-and-dentistry
Scaffold proteins are defined by the presence of specific protein-binding domains (e.g. PDZ domains) that assemble several proteins into functional complexes. |
Scaffold proteins help relay the message between the cell membrane and nucleus faster. ... An example of a GPCR is the β-adrenergic receptor that senses the ... |
Intracellular signaling pathways often use scaffold proteins. Canonical examples include Ste5, essential to the yeast mating MAPK pathway, and KSR, which ... |
Examples like Ste5 in yeast and KSR1 in mammals highlight the importance of scaffold proteins in MAPK pathway regulation. |
20 окт. 2022 г. · Scaffold proteins act as molecular hubs for the docking of multiple proteins to organize efficient functional units for signaling cascades. |
These scaffolds include members of the insulin-receptor substrate (IRS), Dok, FGF-receptor substrate 2, and Shc families (37–41). Once associated with an RTK, ... |
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