A series of new sulfonamide derivatives connected through an imine linker to five or seven membered heterocycles were designed and synthesized. |
This present review summarizes the current innovations of sulfonyl or sulfonamide-based derivatives with potential antibacterial activities |
Aiming to develop new antileishmanial lead compounds, we used a rational approach to synthesize a new set of sulfonamide 4-methoxychalcone derivatives (3a-3i) ... |
Structure activity relationship (SAR) provides insights into the crucial structural components, which are imperative for the biological activity. |
6 окт. 2023 г. · The key structural requirements for antibacterial activity of sulphonamides are: 1) The free amino group (-NH2) on the sulphanilamide ... |
SAR exposed that the sulfonamides with an amino (–NH2) and –NO2 at the para-position of the phenyl ring demonstrated astounding antimicrobial properties. The ... |
24 нояб. 2020 г. · Sulfonamides show some structural similarity with PABA thereby they compete with it and inhibit folic acid synthesis in bacteria. |
Discovery and SAR study of a sulfonamide hydroxamic acid ... pubs.rsc.org › content › articlelanding
Through the use of chemical synthesis and high throughput screening, we discovered a sulfonamide hydroxamic acid inhibitor for the botulinum neurotoxin ... |
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