23 дек. 2009 г. · Overall, the results provide a molecular rationale for observations that the active site tends to be more flexible than the enzyme as a whole, ...

The Equilibrium Model quantitatively explains the effect of temperature on all enzymes for which Vmax can be measured over a range of temperatures [4-7, 9, 11- ...

As the temperature of the enzyme is raised, the flexible active-site region may be deformed and Eact thus converted into Einact with a concomitant reduction in ... INTRODUCTION · RESULTS · DISCUSSION

The results reveal an apparently universal mechanism, independent of enzyme reaction or structure, based at or near the active site, by which enzymes lose ...

As temperature increases so do the rate of enzyme reactions. A ten degree centigrade rise in temperature will increase the activity of most enzymes by 50% ...

This causes the formation of more enzyme-substrate complexes, leading to an increase in enzyme activity.

Importantly, the EM gives rise to a number of new insights into the molecular basis of the temperature control of enzymes and their environmental adaptation ...

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A new understanding of how temperature affects the catalytic activity of enzymes. Michael Danson Trends in Biochemical Sciences, 2010

The rate of an enzyme-catalyzed reaction increases as the temperature is raised. A ten degree Centigrade rise in temperature will increase the activity of most ...