Topiramate was associated with decreased bone formation, which may affect bone strength and BMD with chronic use.

Patients receiving topiramate had higher levels of bone-specific alkaline phosphatase and osteocalcin when compared with controls and higher levels of C- ...

This response was dose dependent for some drugs, e.g. topiramate showed no significant effect on increasing the risk of osteoporosis in lower non-enzyme- ...

23 февр. 2014 г. · Topiramate is known to cause osteoporosis by causing loss of calcium through the kidneys. While osteoporosis is not common, we don't know if it ...

Various studies have indicated a loss of bone density and increased risk of fractures in people using long-term anti-epileptic drugs.

15 июн. 2023 г. · Topiramate may cause osteoporosis (a condition in which bones can break more easily) in adults and rickets (abnormal, curved bone growth) in ...

11 июл. 2024 г. · Using topiramate for a long time may cause the bones to become weaker, leading to reduced bone density (osteopenia). It may also cause a more ...

28 июл. 2010 г. · They told me to drink 3 glasses of milk everyday or take a vitamin D pill because longterm use of the drug affects your bone density.

Topiramate is a newer AED, widely used for migraine prevention, but no evidence is currently available on its effect on bone metabolism.

31 янв. 2024 г. · Other Medical Problems · Bone problems (eg, osteoporosis, osteomalacia, osteopenia) or; Depression, history of or · Diarrhea or · Kidney disease or ...