Normal Function. Collapse Section. The TP53 gene provides instructions for making a protein called tumor protein p53 (or p53) . This protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing (proliferating) too fast or in an uncontrolled way.
1 февр. 2020 г.
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. |
2 окт. 2024 г. · TP53 (Tumor Protein P53) is a Protein Coding gene. Diseases associated with TP53 include Li-Fraumeni Syndrome and Papilloma Of Choroid Plexus. |
The TP53 gene is the most frequently mutated gene (>50%) in human cancer, indicating that the TP53 gene plays a crucial role in preventing cancer formation. Gene · Function · Experimental analysis of p53... |
A gene that makes a protein that is found inside the nucleus of cells and plays a key role in controlling cell division and cell death. |
1 мар. 2023 г. · The tumor suppressor gene TP53 is the most frequently mutated gene in human tumors. The process of tumor development is strongly related to the ... |
TP53 is the most commonly mutated gene in human cancer with over 100,000 literature citations in PubMed. This is a heavily studied pathway in cancer biology and ... |
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. |
TP53 is a gene located on chromosome 17 that encodes a 53-kDa protein involved in regulating various cell cycle processes such as cell death, DNA damage ... |
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