Donepezil was frequently discontinued, and the rate of discontinuation was higher in patients with advanced dementia.

Donepezil was discontinued in 83 (20.9%) patients, most commonly due to an adverse event (43.4%). The mean treatment duration was 103.67 days in patients who ...

18 сент. 2021 г. · The most common reasons for donepezil discontinuation were adverse events in both groups, inability to visit the hospital because of transfers, ...

If the cognitive worsening with discontinuation of donepezil is due to withdrawal from the drug, then halving the donepezil dose before discontinuing it 4 weeks ...

About half of the patients who are prescribed cholinesterase inhibitors, however, discontinue them within a year, apparently because of a perceived lack of ...

11 дек. 2015 г. · It is available as a relatively cheap, generic drug which is often stopped in the later stages of dementia or if symptoms do not improve. A ...

22 окт. 2024 г. · The reasons for discontinuation were a change in the doctors treating the patients (n = 71), ineffectiveness (n = 16), gastrointestinal side- ...

... Discontinuation of drugs might be due to the side effects such as nausea, vomiting, anorexia, diarrhea, bradycardia, dizziness, myalgia, and insomnia caused ...

At her first appointment with the new provider, donepezil 10 mg was discontinued without taper due to the provider's concerns that the VH were an adverse effect ...

Use, however, has not been shown to change the progression of the disease. Treatment should be stopped if no benefit is seen.